A bacteriologist from MIT, Salvador E. Luria's work with Max Delbruck on bacteriophage demonstrated that bacterial resistance to certain phages arose through genetic mutations. His later work showed that phages also mutate genetically. He received the Nobel Prize in Physiology or Medicine in 1969 with Max Delbruck and Alfred D. Hershey. The collection is organized into seven series: I. Correspondence, 1938-1992 ; IIa. Subject Files, 1938-1990 ; IIb. Personal Material. 1923-1991 ; III. Works by Luria, 1938-1987 ; IV. Works by Others, 1944-1990 ; V. Research Notes and Notebooks, 1941-1979 ; VI. Course Material, 1931-1991 ; VII. Photographs and Negatives, 1957-1982. Arrangement: Alphabetical by folder title and then chronological within each folder.

Working on bacterial viruses in 1945, Seymour S. Cohen offered the first systematic exploration of the biochemistry of virus-infected cells and of how viruses multiply. His subsequent research included delineating the phenomenon of thymineless death, developing derivatives of ara-A compound, working on RNA synthesis, studying the effects of polyamines on metabolic systems, and studying plant viruses (including viral cations). Much of his research has contributed to the chemical treatment of cancer and viral infections.